27 7 / 2014

Permalink 7,350 notes

26 7 / 2014

leonkumquat:

when my dad was in college he had a friend who told a girl he’d take her on a date unlike any other she’d ever been on and so he took her to the supermarket to watch the lobsters fighting in the lobster tank

they’re married now

(via realitycheckeveryday)

Permalink 171,840 notes

26 7 / 2014

"Just because your pain is understandable, doesn’t mean your behavior is acceptable."

Steve Maraboli, Unapologetically You: Reflections on Life and the Human Experience (via derikisu)

Keep this one in your back pocket for the next time someone acts like an ass and then tells you they’ve been through a lot of stuff. Respectful and yet still firmly keeping respect for yourself. 

(via emilyvgordon)

(Source: quotes-shape-us, via waesosirious)

Tags:

Permalink 171,190 notes

26 7 / 2014

whataboutwriting:

Also, do you have any tips on staying focused when writing?
  • Find a workplace. Some people can only work efficiently in certain places. Certain environments will boost your productivity, while others will completely ruin it. Find the places where you’re the most…

Permalink 3,134 notes

26 7 / 2014

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26 7 / 2014

irwinelgortwatersstyles:

nosdrinker:

i don’t know what these are but i love them

those are cows, washed and blow dried.

(Source: weeaboo-chan, via realitycheckeveryday)

Permalink 115,782 notes

26 7 / 2014

wildstag:

untitled by herax on Flickr.

wildstag:

untitled by herax on Flickr.

(via emptyforest)

Permalink 111 notes

26 7 / 2014

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26 7 / 2014

taming-the-fox:

hankgreensmoustache:

champagne-paradise:

kaworushin:

wouldnt it be fucking scary if you had a clock that counted down until the moment you die. like what if it could be altered too like one day it says 70 years left but then you do something and it says 10 minutes left and youre like what the fuck i fucked up i fucked up i fucked up

omg

what if you got on a plane and then as soon as it took off everybodys clock changed to 20 minutes

Someone write a book

(Source: darmani-remade, via realitycheckeveryday)

Permalink 606,502 notes

26 7 / 2014

Freedom without any purpose feels a whole lot like boredom.

(Source: kupater, via jihho)

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24 7 / 2014

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24 7 / 2014

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24 7 / 2014

rosswoodpark:

crusherccme:

found this gem in the 1996 Cornell Women’s Handbook. it’s what to say when a guy tries to get out of using a condom

"It takes too long"So does raising a fucking child

rosswoodpark:

crusherccme:

found this gem in the 1996 Cornell Women’s Handbook. it’s what to say when a guy tries to get out of using a condom

"It takes too long"
So does raising a fucking child

(via realitycheckeveryday)

Permalink 281,465 notes

24 7 / 2014

psych2go:

For more posts like these, go visit psych2go
Psych2go features various psychological findings and myths. In the future, psych2go attempts to include sources to posts for the for the purpose of generating discussions and commentaries. This will give readers a chance to critically examine psychology.

Fact submitted by: daenerysanddestiel

psych2go:

For more posts like these, go visit psych2go

Psych2go features various psychological findings and myths. In the future, psych2go attempts to include sources to posts for the for the purpose of generating discussions and commentaries. This will give readers a chance to critically examine psychology.

Fact submitted by: daenerysanddestiel

Permalink 1,506 notes

24 7 / 2014

neurosciencestuff:

Stress tied to change in children’s gene expression related to emotion regulation, physical health
Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems. In a new study, scientists have found that maltreatment affects the way genes are activated, which has implications for children’s long-term development. Previous studies focused on how a particular child’s individual characteristics and genetics interacted with that child’s experiences in an effort to understand how health problems emerge. In the new study, researchers were able to measure the degree to which genes were turned “on” or “off” through a biochemical process called methylation. This new technique reveals the ways that nurture changes nature—that is, how our social experiences can change the underlying biology of our genes.
The study, from researchers at the University of Wisconsin, Madison, appears in the journal Child Development. Nearly 1 million children in the United States are neglected or abused every year.
The researchers found an association between the kind of parenting children had and a particular gene (called the glucocorticoid receptor gene) that’s responsible for crucial aspects of social functioning and health. Not all genes are active at all times. DNA methylation is one of several biochemical mechanisms that cells use to control whether genes are turned on or off. The researchers examined DNA methylation in the blood of 56 children ages 11 to 14. Half of the children had been physically abused.
They found that compared to the children who hadn’t been maltreated, the maltreated children had increased methylation on several sites of the glucocorticoid receptor gene, also known as NR3C1, echoing the findings of earlier studies of rodents. In this study, the effect occurred on the section of the gene that’s critical for nerve growth factor, which is an important part of healthy brain development.
There were no differences in the genes that the children were born with, the study found; instead, the differences were seen in the extent to which the genes had been turned on or off. “This link between early life stress and changes in genes may uncover how early childhood experiences get under the skin and confer lifelong risk,” notes Seth D. Pollak, professor of psychology and pediatrics at the University of Wisconsin, Madison, who directed the study.
Previous studies have shown that children who have experienced physical abuse, sexual abuse, and neglect are more likely to develop mood, anxiety, and aggressive disorders, as well as to have problems regulating their emotions. These problems, in turn, can disrupt relationships and affect school performance. Maltreated children are also at risk for chronic health problems such as cardiac disease and cancer. The current study helps explain why these childhood experiences can affect health years later.
The gene identified by the researchers affects the hypothalamic-pituitary-adrenal (HPA) axis in rodents. Disruptions of this system in the brain would make it difficult for people to regulate their emotional behavior and stress levels. Circulating through the body in the blood, this gene affects the immune system, leaving individuals less able to fight off germs and more vulnerable to illnesses.
"Our finding that children who were physically maltreated display a specific change to the glucocorticoid receptor gene could explain why abused children have more emotional difficulties as they age," according to Pollak. "They may have fewer glucocorticoid receptors in their brains, which would impair the brain’s stress-response system and result in problems regulating stress."
The findings have implications for designing more effective interventions for children, especially since studies of animals indicate that the effects of poor parenting on gene methylation may be reversible if caregiving improves. The study also adds to what we know about how child maltreatment relates to changes in the body and mind, findings that were summarized recently in an SRCD Social Policy Report by Sara R. Jaffee and Cindy W. Christian.

neurosciencestuff:

Stress tied to change in children’s gene expression related to emotion regulation, physical health

Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems. In a new study, scientists have found that maltreatment affects the way genes are activated, which has implications for children’s long-term development. Previous studies focused on how a particular child’s individual characteristics and genetics interacted with that child’s experiences in an effort to understand how health problems emerge. In the new study, researchers were able to measure the degree to which genes were turned “on” or “off” through a biochemical process called methylation. This new technique reveals the ways that nurture changes nature—that is, how our social experiences can change the underlying biology of our genes.

The study, from researchers at the University of Wisconsin, Madison, appears in the journal Child Development. Nearly 1 million children in the United States are neglected or abused every year.

The researchers found an association between the kind of parenting children had and a particular gene (called the glucocorticoid receptor gene) that’s responsible for crucial aspects of social functioning and health. Not all genes are active at all times. DNA methylation is one of several biochemical mechanisms that cells use to control whether genes are turned on or off. The researchers examined DNA methylation in the blood of 56 children ages 11 to 14. Half of the children had been physically abused.

They found that compared to the children who hadn’t been maltreated, the maltreated children had increased methylation on several sites of the glucocorticoid receptor gene, also known as NR3C1, echoing the findings of earlier studies of rodents. In this study, the effect occurred on the section of the gene that’s critical for nerve growth factor, which is an important part of healthy brain development.

There were no differences in the genes that the children were born with, the study found; instead, the differences were seen in the extent to which the genes had been turned on or off. “This link between early life stress and changes in genes may uncover how early childhood experiences get under the skin and confer lifelong risk,” notes Seth D. Pollak, professor of psychology and pediatrics at the University of Wisconsin, Madison, who directed the study.

Previous studies have shown that children who have experienced physical abuse, sexual abuse, and neglect are more likely to develop mood, anxiety, and aggressive disorders, as well as to have problems regulating their emotions. These problems, in turn, can disrupt relationships and affect school performance. Maltreated children are also at risk for chronic health problems such as cardiac disease and cancer. The current study helps explain why these childhood experiences can affect health years later.

The gene identified by the researchers affects the hypothalamic-pituitary-adrenal (HPA) axis in rodents. Disruptions of this system in the brain would make it difficult for people to regulate their emotional behavior and stress levels. Circulating through the body in the blood, this gene affects the immune system, leaving individuals less able to fight off germs and more vulnerable to illnesses.

"Our finding that children who were physically maltreated display a specific change to the glucocorticoid receptor gene could explain why abused children have more emotional difficulties as they age," according to Pollak. "They may have fewer glucocorticoid receptors in their brains, which would impair the brain’s stress-response system and result in problems regulating stress."

The findings have implications for designing more effective interventions for children, especially since studies of animals indicate that the effects of poor parenting on gene methylation may be reversible if caregiving improves. The study also adds to what we know about how child maltreatment relates to changes in the body and mind, findings that were summarized recently in an SRCD Social Policy Report by Sara R. Jaffee and Cindy W. Christian.

Permalink 408 notes